I’ve always used ibuprofen (Advil, Motrin) in the past, but I’m reconsidering this based on the recent finding.

High doses of naproxen (Aleve) are not associated with increased cardiovascular risk (good news), while other non-steroidal antiflammatory drugs (NSAIDs), including ibuprofen and diclofenac caused an average of three extra major vascular events each year for every 1,000 patients treated.

Both ibuprofen and naproxen still do increase the risk of GI bleeding about 3 fold compared to placebo.